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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK1
All Species:
21.21
Human Site:
T415
Identified Species:
38.89
UniProt:
Q96SB4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SB4
NP_003128.3
655
74325
T415
S
Q
E
T
D
S
C
T
P
I
T
S
E
V
S
Chimpanzee
Pan troglodytes
XP_518428
831
92792
T591
S
Q
E
T
D
S
C
T
P
I
T
S
E
V
S
Rhesus Macaque
Macaca mulatta
XP_001116721
831
92803
T591
S
Q
E
T
D
S
C
T
P
I
K
S
E
V
S
Dog
Lupus familis
XP_850330
823
92006
T583
S
Q
E
T
D
S
C
T
P
I
T
S
E
V
S
Cat
Felis silvestris
Mouse
Mus musculus
O70551
648
73070
T415
S
Q
D
T
D
S
C
T
P
T
A
S
E
T
M
Rat
Rattus norvegicus
NP_001020897
655
73837
T415
S
P
E
T
D
S
C
T
P
S
G
S
E
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516210
528
59280
D331
I
R
A
E
I
P
S
D
D
E
N
E
N
N
G
Chicken
Gallus gallus
XP_419265
754
84415
S516
P
R
A
A
V
S
D
S
F
V
P
L
V
S
E
Frog
Xenopus laevis
NP_001085122
605
68633
H390
Q
T
S
T
V
Q
P
H
K
H
N
E
N
E
E
Zebra Danio
Brachydanio rerio
NP_001074138
640
71523
L399
T
E
P
S
P
A
C
L
S
A
A
D
G
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
M573
S
R
E
E
I
K
I
M
A
Q
H
A
V
V
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
L230
D
L
K
P
E
N
I
L
L
V
S
S
D
Y
V
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
D489
S
N
N
N
N
N
E
D
I
M
N
T
P
L
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
78.2
76.7
N.A.
91.4
91.4
N.A.
65.5
70.1
67.6
64.7
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
100
78.6
78.5
77.6
N.A.
94.6
94
N.A.
70.3
77.3
78.1
76.1
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
66.6
73.3
N.A.
0
6.6
6.6
6.6
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
73.3
73.3
N.A.
6.6
26.6
6.6
33.3
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
0
8
0
0
8
8
16
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
54
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
47
0
8
16
8
0
0
8
8
0
0
% D
% Glu:
0
8
47
16
8
0
8
0
0
8
0
16
47
8
16
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
16
% G
% His:
0
0
0
0
0
0
0
8
0
8
8
0
0
0
8
% H
% Ile:
8
0
0
0
16
0
16
0
8
31
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
8
0
0
8
0
8
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
16
8
0
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
8
% M
% Asn:
0
8
8
8
8
16
0
0
0
0
24
0
16
16
0
% N
% Pro:
8
8
8
8
8
8
8
0
47
0
8
0
8
0
8
% P
% Gln:
8
39
0
0
0
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
62
0
8
8
0
54
8
8
8
8
8
54
0
8
31
% S
% Thr:
8
8
0
54
0
0
0
47
0
8
24
8
0
8
0
% T
% Val:
0
0
0
0
16
0
0
0
0
16
0
0
16
47
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _